Skin and brain: a common origin
This connection goes back to an embryo’s 21st day of life. This is the moment when the outermost cellular layer, the ectoderm, gives birth to both the nervous system and the epidermis.
Neuromediators are the words used by the skin and the brain
If communication takes place, then a language exists. A language is formed of words.
Neuromediators are the words used by of our skin and our brain. Dozens of them are common to both.
As messengers, neuromediators can exercise direct influence over both our skin and our emotions.
Four cutaneous neuromediators are at the heart of the skin and brain language
Our Research Laboratories have targeted four key messengers.
On the skin, it has a protective and regenerating effect on the skin.
On the skin, it has a protective and regenerating effect.
When released in excess, it causes stress. On the skin, it weakens the cutaneous barrier.
On the skin, it causes stress.
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At the core of all NEURAÉ skincare
Is our innovative NA3™ Technology.
Developed in our research Laboratories,
it is activated via three complementary neuromodulative components:
Neuro-actives
Innovative active ingredients to promote positive messagers and limit negative ones on the skin :
_ The stimulating Red Indigo extract of natural origin, promotes production of the β-endorphin* and limits cortisol* production to reduce the signs of fatigue.
_ The beneficial Alpine Skullcap extract of natural origin, promotes production of the β-endorphin and activates GABA* receptors to boost the skin’s well-being.
_ The soothing Eperua extract of natural origin, Limits CGRP* production for that feels more zen and relaxed.
Our Serum is the starting point for each of our routines: énergie, joie and sérénité.
It is formulated from a unique patent-pending complex of neuro-active ingredients.
* in vitro test on the ingredient
Neuro-fragrances
Our four fragrances were created in line with the aromachology principles.
Their composition blends essential oils and fragrance compounds, selected for their aromatherapeutic effects, in order to trigger the appropriate emotional response.
To scientifically prove their impact on our emotional well-being, our neuro-fragrances were all tested using innovative neuroscientific methodologies.
Neuro-textures
Our neuroscientific tests have proven that the textures themselves provoke an emotional response. Blank/Mock textures were tested using Implicit Response Time or IRT to identify their emotional profiles.
We believe in… a science based on innovative tests
It started intuitively: we believed it was possible to use neuromodulating active ingredients to impact skin and emotions through a new vision of cosmetics elevated by neuroscience. To verify the theory, Sisley Laboratories worked with expert partners to establish an innovative testing programme.
The results exceeded the team’s expectations.
TESTS ON THE CELLS
Conducted using a technique inspired by a Nobel Prize in medicine, the tests have been the subject of cutting-edge methodology including a 3D model of a reconstructed epidermis and sensory neurons, assessing and confirming the effectiveness of NEURAÉ’s neuro-ingredients.
TESTS ON THE SKIN
In total, 140 people took part in clinical skin trials. The tolerance of the products has been tested under dermatological control. A series of instrumental measurements and analyses were performed to observe NEURAÉ’s effects on skin. Voluntary participants also conducted self-assessment to judge a multitude of effects (tired features, quality of skin texture, radiance, etc.).
TESTS ON EMOTIONS
In total, 180 people took part in clinical neuroscientific trials. To measure and objectify emotions, tests were carried out to observe panelists' reactions on two levels:
Physiological: through the variations in heart rhythm and facial analysis (measuring basic emotions such as joy and sadness)
Psychological: using implicit measurements and explicit measurements using questionnaires.